Vol. 19 No. 1 (2020) | Tropical Journal of Pharmaceutical Research

Published: 2020-04-09

Formulation, characterization and wound-healing potential of emulgel and in-situ gel containing root extract of Saussurea lappa Clarke (Asteraceae)

Aitazaz Ahsan, Ghulam A. Miana, Humaira Naureen, Masood U. Rehman, Kamil Anum, Imran Malik

1-9

DOI:

10.4314/tjpr.v19i1.1

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Potentiation of raloxifene cytotoxicity against MCF-7 breast cancer cell lines via transdermal delivery and loading on self-emulsifying nanoemulsions

Hibah M. Aldawsari, Aya A. Negm

11-15

DOI:

10.4314/tjpr.v19i1.2

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Cytotoxic, colony formation and anti-migratory effects of Spilanthes acmella (Asteraceae) aerial extract on MCF-7 cells and its cream formulation

Supavadee Boontha, Thatcha Thoedyotin, Thanaphon Saengtabtim, Pathitta Im-erb, Natthamon Chaniad, Benjaporn Buranrat, Tasana Pitaksuteepong

17-24

DOI:

10.4314/tjpr.v19i1.3

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α-Mangostin protects against myocardial ischemia reperfusion injury by suppressing the activation of HIF-1α

Hong Jiang, Wenli Guo, Dongdong Zhu, Wei Zhang, Jing Yu, Manli Feng, Xiaoyu Wang, Xiaopeng Wang, Yanan Jiao, Chengcheng Wang, Yan Chen

25-31

DOI:

10.4314/tjpr.v19i1.4

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In vitro alteration of artemisinin biosynthesis in Artemisia annua L during treatment with methyl jasmonate

Pravej Alam, Thamer H. Albalawi

33-37

DOI:

10.4314/tjpr.v19i1.5

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MiR-196b-5p regulates the proliferation of drug-resistant hepatocellular carcinoma cell lines by activating NFκB/ABCB1 signaling pathway

Bangming Pu, Yong Cao, Yan Li, Li Tang, Jiyi Xia, Bo Li

39-44

DOI:

10.4314/tjpr.v19i1.6

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Determination of radical scavenging activities of some pyrimidine derivatives

Oluwole S. Aremu, Lebogang Katata-Seru, Olukayode O. Aremu, Constance R. Sewani-Rusike, Neil Koorbanally

45-49

DOI:

10.4314/tjpr.v19i1.7

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Imidazole-thiazolidinone inhibits oesophageal cancer cell proliferation via induction of apoptosis and cell cycle arrest at S phase

Qian Wang, Yuan Yuan, Mi Jiang, Lihua Huang, Jie Huang, Hongyuan Shen

51-56

DOI:

10.4314/tjpr.v19i1.8

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Schisandra chinensis extract ameliorates myocardial ischemia/reperfusion injury via TLR4/NF-κB/MyD88 signaling pathway

Yang Lou, Bo Xu, Xianshuai Li, Xiaoyi Xu, Xiaoguo Chen

57-62

DOI:

10.4314/tjpr.v19i1.9

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Protective effect of ginkgolide B against isoproterenolinduced chronic heart failure in rats via modulation of Nrf2 and HO-1 signaling pathways

Lu Hui Zhi, Wang Bin Ru, Tan Yun, Dong Hui, Liu Li

63-69

DOI:

10.4314/tjpr.v19i1.10

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Farrerol ameliorates diabetic hepatopathy in rat model of type 2 diabetes mellitus via modulation of oxidativeinflammatory stress

Li Dong, Lixia Yang, Fengsui Liu, Haitao Zhan, Xinwei Chen

71-76

DOI:

10.4314/tjpr.v19i1.11

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Effects of mTOR inhibitor, everolimus, on proliferation, autophagy and temozolomide sensitivity of glioma cells

Wei Dong, Jialiang Wang, Haipeng Liu, Shuo Sun, Yanbin Wang

77-82

DOI:

10.4314/tjpr.v19i1.12

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Bethanechol versus selegiline in amelioration of spinal cord injury in a rat model: A potential therapeutic option in spinal cord injury treatment

Guangliang Fan, Jinli Luan, Xiankuo Tang, Qimin Song

83-87

DOI:

10.4314/tjpr.v19i1.13

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Mangiferin ameliorates insulin resistance in a rat model of polycystic ovary syndrome via inhibition of inflammation

Qiaohong Qian, Minjie Tang, Xinrong Li, Qi Cao, Zhiling Zhu

89-94

DOI:

10.4314/tjpr.v19i1.14

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Constipation-relieving effect of L-arabinose

Hao Wang; Wenxian Zhang; Bin Jiang

95-99

DOI:

10.4314/tjpr.v19i1.15

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Anti-glioma effect of 7-H-pyrrolo [2,3-di]pyrimidine derivative via induction of cell death

Jie Wang, Xiang Peng, Chengan Cao, Yan Zhao, Xing Xia

101-106

DOI:

10.4314/tjpr.v19i1.16

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Compound xiebai capsule alleviates pulmonary vascular remodeling in monocrotaline-induced pulmonary arterial hypertension in rats

Zhouye Wu, Zhaoqing Xi

107-114

DOI:

10.4314/tjpr.v19i1.17

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Baicalein inhibits the invasion of human cervical cancer cells by inhibiting the hedgehog/Gli signaling pathway

Hai Yang, Jiyi Xia, Yan Li, Yong Cao, Li Tang, Xiaolan Yu

115-120

DOI:

10.4314/tjpr.v19i1.18

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Radioprotective and anti-diabetic effects of Costus speciosus and carnosine

Ebtisam A. Marzook, Fawzy A. Marzook, Ahmed E. Abd El Moneim

121-127

DOI:

10.4314/tjpr.v19i1.19

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Anticancer property of hexane extract of Suaeda fruticose plant leaves against different cancer cell lines

Kamel A. Saleh, Tahani H Albinhassan, Adel M. Al-Ghazzawi, Abdulrahman Mohaya, Ali A. Shati, Huda J. Ayoub, Qasem M. Abdallah

129-136

DOI:

10.4314/tjpr.v19i1.20

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In vivo antimalarial effect of Ananas comosus (L) Merr (Bromeliaceae) fruit peel, and gas chromatography-mass spectroscopy profiling: A possible role for polyunsaturated fatty acid

Philip F. Uzor, Blessing U Ishiwu, Ngozi J. Nwodo

137-145

DOI:

10.4314/tjpr.v19i1.21

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Synthesis, characterization and evaluation of antiinflammatory properties of novel α, β-unsaturated ketones

Leaqaa A. Alrubaie, Raheem J. Muhasin, Mazin N. Mousa

147-154

DOI:

10.4314/tjpr.v19i1.22

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Immunoprotective evaluation of Escherichia coli outer membrane protein A against the main pathogens of animal mastitis

Chen Chen, Nana Wu, Na Rong, Chao Kang, Chunlin Chen, Sanqiao Wu, Xiang Liu, Xiaoying Zhang

155-162

DOI:

10.4314/tjpr.v19i1.23

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In vitro evaluation of the inhibitory effect of 3, 5-dichloro-2- pyridone on Mycobacterium tuberculosis H37Rv

Lin Ling, Chen Ling, Hua Wu

163-168

DOI:

10.4314/tjpr.v19i1.24

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In-silico design of novel 4-aminoquinolinyl analogs as potential anti-malaria agents using quantitative structure– activity relationships and ADMET approach

Bo Wu, Jiao-Long Wang, Liang Li, Chun-Jie Wu, Chong-Bo Zhao

169-181

DOI:

10.4314/tjpr.v19i1.25

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Comparison of efficacy and safety of teriparatide and hyaluronic acid - calcitonin combination treatments in Chinese osteoporotic patients with risk of bone fracture: A preliminary investigation

Changju Hou

183-188

DOI:

10.4314/tjpr.v19i1.26

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Efficacy and safety of VEGFR inhibitors versus standard chemotherapy in Chinese patients with metastatic liver cancer: Results of a preliminary clinical trial

Dong Qian, Shuai Wang, Hongzhi Zhao, Chen Zhang

189-194

DOI:

10.4314/tjpr.v19i1.27

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Methylenetetrahydrofolate reductase polymorphism and capecitabine-induced toxicity in patients with gastric cancer

Xiong-wei Xie, Mao-ren Wang, Yong-lian Zhang

195-199

DOI:

10.4314/tjpr.v19i1.28

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A clinical study of drugs associated with acute kidney injury in the Chinese population

Xiaoting Xu, Haiping Yu

201-208

DOI:

10.4314/tjpr.v19i1.29

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Methylenetetrahydrofolate reductase C677T polymorphism and toxicity to 5-FU-based chemotherapy in colorectal cancer
Methylenetetrahydrofolate reductase C677T polymorphism and toxicity to 5-FU-based chemotherapy in colorectal cancer

Yong-lian Zhang, Xiong-wei Xie

209-213

DOI:

10.4314/tjpr.v19i1.30

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