An Evaluation of Effects Of Platelet‑rich‑fibrin on Postoperative Morbidities after Lower Third Molar Surgery

Abstract

Objectives: The aim of the present study was to assess whether the use of
platelet‑rich fibrin (PRF) decreased the pain, swelling, and trismus levels of
postoperative third molar surgery. Materials and Methods: In a double‑blinded,
split‑mouth randomized study, thirty patients (6 male/24 female, mean age
20.32 years) with bilateral symmetric impacted third molars were enrolled
in this study to receive surgery. The PRF mass was randomly placed in one of
the extraction sockets, whereas the other socket was left without treatment.
The outcome variables were pain, maximum mouth opening (trismus),
swelling (edema), and the presence of dry socket which were measured using a
10‑point visual analog scale, manual calipers, and 3dMD facial imaging system
which was used for the 1st time in the third molar surgery. Results: Statistical
analyses revealed that there were no significant differences between the control
and study groups regarding postoperative pain, swelling, and trismus (P > 0.05).
Conclusion: The results of this study suggest that PRF was not observed to have
a positive effect on postoperative discomfort, so even though, PRF is presumed to
have positive effects on healing and recovery processes.

Keywords: 3dMD, pain, platelet‑rich fibrin, swelling, third molar surgery, trismus