Pattern Of dyslipidaemia among Nigerians with type 2 diabetes mellitus

Abstract

To characterize the pattern of lipid profile abnormalities among Nigerians with type 2 diabetes mellitus attending theDiabetes clinic of a tertiary referral centre in Nigeria. Across sectional analysis of 192 diabetic patients consecutively recruited frompatients attending the Diabetes clinic and 52 volunteering non-diabetic and non-hypertensive controls was undertaken. The main outcome measures were lipid profile and anthropometric indices. Data analysis was done with SPSS version 10.Resultswere expressed asmean ± SD.Differences between groupswere regarded as significant at p < 0.05. Comparisons of means, test of association were done using independent t-test, chi-square test and bivariate (Pearson\'s) correlation analysis. Eighty-nine percent of the patients had at least one abnormal lipid profile while 64.5%had combined dyslipidaemia. Reduced HDL-C and raised TG constituted the most (88.0%) and least (25.0%) prevalent abnormalities respectively. Significant difference in the mean values of HDL-C and LDL-C was observed between the patients and controls. Dyslipidaemia is common among patients with type 2 diabetes mellitus in Nigeria with majority of the patients having a combined dyslipidaemia. There is therefore the need to pay great attention to the lipid parameters inNigerianswith type 2 diabetesmellitus. TG Triglycerides, TC total cholesterol, LDL-C Low Density Lipoprotein Cholesterol, HDL-C High Density Lipoprotein Cholesterol, WC Waist circumference, HC Hip circumference, BMI Bodymass index,WHR Waist-hip ratio.



Nigerian Journal of Clinical Practice Vol. 11 (1) 2008: pp.25-31