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Published:
Feb 22, 2005Keywords:
Squamous cell carcinoma invasive conjunctiva orbito-ocular tumours intraorbital intraocular extensions
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Squamous Cell Carcinoma Of The Conjunctivain Benin City, Nigeria
Abstract
Aims: To find out the incidence and mode of presentation of squamous cell carcinoma of the conjuctiva at the University of Benin Teaching Hospital, Benin City, Nigeria and to note any associated or predisposing factors.
Materials and Methods: The case records of all patients diagnosed as squamous cell carcinoma and carcinoma in situ of the conjunctiva by the Pathology Department of the University of Benin Teaching Hospital over an eight year period from January 1990 to December 1997 were reviewed.
Results: Nine patients (seven males and two females) with squamous cell carcinoma of the conjunctiva were seen during this period. These constituted 20.5% of all cases of orbito-ocular tumours seen during the period. There were two cases of carcinoma in situ and seven cases of invasive squamous cell carcinoma with intraocular extension.
The age range was 20-70 years with a mean age of 24 years. Late presentation of the patients was noted. Excision of the tumour was the treatment of choice in the patients with carcinoma in situ while patients with intraocular extension of the tumour had enucleation and adjunct radiotherapy.
Conclusion: Squanous call carcinoma of the conjuctiva is a very aggressive disease in Benin City, Nigeria. Most of the patients presented late with marked intraocular extension so that enucleation of the eye is usually the treatment of choice. Possible associated factors include exposure to ultra violet radiation and human immune deficiency virus (HIV) seropositivity.
KEY WORDS: Squamous cell carcinoma; invasive, conjunctiva, orbito-ocular, tumours, intraorbital, intraocular, extensions.
Nigerian Journal of Clinical Practice Vol.5(2) 2002: 143-147
Materials and Methods: The case records of all patients diagnosed as squamous cell carcinoma and carcinoma in situ of the conjunctiva by the Pathology Department of the University of Benin Teaching Hospital over an eight year period from January 1990 to December 1997 were reviewed.
Results: Nine patients (seven males and two females) with squamous cell carcinoma of the conjunctiva were seen during this period. These constituted 20.5% of all cases of orbito-ocular tumours seen during the period. There were two cases of carcinoma in situ and seven cases of invasive squamous cell carcinoma with intraocular extension.
The age range was 20-70 years with a mean age of 24 years. Late presentation of the patients was noted. Excision of the tumour was the treatment of choice in the patients with carcinoma in situ while patients with intraocular extension of the tumour had enucleation and adjunct radiotherapy.
Conclusion: Squanous call carcinoma of the conjuctiva is a very aggressive disease in Benin City, Nigeria. Most of the patients presented late with marked intraocular extension so that enucleation of the eye is usually the treatment of choice. Possible associated factors include exposure to ultra violet radiation and human immune deficiency virus (HIV) seropositivity.
KEY WORDS: Squamous cell carcinoma; invasive, conjunctiva, orbito-ocular, tumours, intraorbital, intraocular, extensions.
Nigerian Journal of Clinical Practice Vol.5(2) 2002: 143-147
