Bilateral pelvi.ureteric junction obstruction: Our experience in a developing country

Abstract

Background: Bilateral pelvi.ureteric junction (PUJ) obstruction is rare and causes high morbidity and mortality. Recent advances have led to its diagnosis and management in the perinatal period. However, open surgery is still the mainstay of treatment in less endowed nations where late presentation is the norm.
Materials and Methods: All patients with PUJ obstruction diagnosed and managed at the University of Maiduguri Teaching Hospital between January 2006 and December 2011 were retrospectively reviewed. All had open  surgery and all repairs were stented with double J stents or appropriate size feeding tube.
Results: A total of 18 patients were analyzed, 11 males and 7 females with a ratio of 1.57:1 and mean age of 27.5 years (age range 2.38). The main clinical features were loin pain (72.22%) and fever (72.22%); while the main complications at presentation were hydronephrosis (55.56%),  impaired renal function (61.11%) and pyelonephritis (50%). The causes of obstruction were mainly congenital (50.0%) and due to schistosomal fibrosis/stricture (22.2%). Preliminary double J stents, tube nephrostomies and hemodialysis were used to recover renal function before surgery. Anderson.Hynes (41.7%) and Heineke.Mirhulicz (19.4%) pyeloplasty were the main procedures performed. The main post.operative complications were urinary tract infections (67.67%) and leakage (11.11%). The mean duration of symptoms was 23.72 months and the mean hospital stay was 13 days. The mortality rate was 5.56%.
Conclusion: Bilateral PUJ obstruction is uncommon in Maiduguri, with  congenital causes and schistosomal fibrosis as the most common  etiologies. Aggressive treatment aimed at recovering renal function is necessary before open pyeloplasty if morbidity and mortality is to be reduced. Open pyeloplasty remained the best treatment option with favorable outcome.

Key words: Bilateral pelviureteric junction obstruction, causes,  management, outcome