Renal Dysfunction Among Stroke Patients, Hospital Based Cross Sectional Study, Addis Ababa, Ethiopia, 2021

Abstract

Background: - Stroke is the leading explanation for neurological disability and the second commonest cause of death in the world. Even  though renal dysfunction is among commonly encountered comorbidity in acute stroke patients, there was no data on the prevalence  and associated factors of renal dysfunction among acute stroke patients in Ethiopia.

Objective: This study aimed to determine the magnitude of renal dysfunction and factors associated with renal dysfunction among  hospitalized acute stroke patients.

Method: Hospital based retrospective cross sectional study wasonducted among all acute stroke  patients admitted to Saint Peter’s specialized hospital from January to December 2021. The Data were collected from patient medical  charts using a structured checklist. SPSS 23.0 was used to analysis the collected data. In order to evaluate the factors associated with  renal dysfunction, statistical logistic regression with a level of α set at 0.05 was employeed. For variables with a p<0.05, statistical  significance was considered.

Result: The study included 118 acute stroke patients, with a mean and standard deviation age of 60.1±14.9  years, and 63(53.4%) were males. 22 (18.6%) of the study, population had renal dysfunction. Males were more commonly 12(54.5%)  affected than females. Diabetes mellitus had statistically significant association with renal dysfunction (p=0.031). Patients who had renal  dysfunction had a higher mortality rate (31.8%) as compared with patients with normal renal function (21.9%).

Conclusion: Renal  dysfunction is a frequent comorbidity in patients who are admitted with the diagnosis of acute stroke and had a higher mortality rate  than stroke patients with normal renal function.