Treatment of diabetic neuropathy in the lower limb: Signs and symptoms of diabetic neuropathy may precede the onset of diabetes.

Abstract

Diabetic peripheral neuropathy (DPN) is defined as ‘the presence of symptoms and/or signs of peripheral nerve dysfunction in people with diabetes after exclusion of other causes: the diagnosis cannot be made without a clinical examination’. In fact, many of these symptoms and signs may precede the onset of diabetes.