The Association of Microalbuminuria with Severity of Coronary Artery Disease Detected by Angiography in Type II Diabetes

Abstract

Background: One of the strongest risk factors for coronary artery disease is diabetes mellitus. Therefore, it is crucial to identify CAD in  diabetic patients as soon as feasible. This study aimed to assess the relation between microalbuminuria and the angiographic severity of  CAD patients with type 2 DM by SYNTAX I, SYNTAX II and Gensini scores.

Patients and Methods: The study comprised 82 type II DM  patients who were referred for elective coronary angiography due to a suspected CAD. All patients had their urinary albumin-creatinine  ratio (UACR) determined, and the Gensini, SYNTAX, and SYNTAX II scores were used to determine how severe each patient's CAD was.  

Results: There were 26 (31.7%) females and 56 (68.3%) males in the study population. They were 56.29 + 9.18 years old on average.  According to the UACR level, patients were divided into two groups: group 1 included patients with UACR less than 30 mg/g (41 patients),  and group 2 included patients with UACR greater than or equal to 30 mg/g (41 patients). According to the study, patients in group 2 had considerably higher Gensini scores than patients in group 1 (P=0.001) and significantly higher SYNTAX scores than patients in group 1  (P=0.001). Age and the duration of DM and UACR had a positive association (p=0.003), and hypertension (HTN) and the duration of DM  and UACR had a positive correlation (p=0.049).

Conclusion: In type II DM, microalbuminuria can be utilized to predict the presence and  severity of CAD.