https://www.ajol.info/index.php/zjps/issue/feed 2023-11-10T09:51:29+00:00 Professor Islam Ibrahim eaebrahiem@pharmacy.zu.edu.eg Open Journal Systems <p>Focus and scope of journal</p> <p>Zagazig Journal of Pharmaceutical Sciences (ZJPS), an open-access biannual peer-reviewed scientific journal, is the official journal of the Faculty of Pharmacy, Zagazig University.</p> <p>The aim of ZJPS is the international coverage of significant scientific advances in various disciplines of pharmaceutical sciences and related subjects. It publishes high-quality original research, reviews, mini-reviews, case reports, letters to the editor, opinions, commentaries, conference abstracts, and preprints. The scope of ZJPS includes the following disciplines:</p> <ol> <li>Pharmacology &amp; Toxicology.</li> <li>Pharmaceutics.</li> <li>Pharmacy Practice</li> <li>Pharmacognosy</li> <li>Microbiology &amp; Immunology</li> <li>Biochemistry</li> <li>Pharmaceutical Chemistry.</li> </ol> <p>You can view this journal's website <a href="https://zjps.journals.ekb.eg/" target="_blank" rel="noopener">here</a>.</p> https://www.ajol.info/index.php/zjps/article/view/259005 2023-11-10T09:34:28+00:00 Eman A. Madbouly EAMadbouli@pharmacy.zu.edu.eg Sobhy M. El-adl EAMadbouli@pharmacy.zu.edu.eg Abdalla A. El-Shanawany EAMadbouli@pharmacy.zu.edu.eg

<p>The quickest methods for battling the new coronavirus pandemic at the beginning of the COVID-19 outbreak were&nbsp; therapeutic treatments based on approved drugs. Although there are now many vaccines available, it will take time for&nbsp; the global vaccination program to take effect. Therefore, in addition to vaccination, repurposing currently available&nbsp; antiviral, antibiotic, and other types of medications has been suggested as a complementary medical strategy for&nbsp; COVID19 infections. Analytical methods for assessing drug concentrations in biological fluids and pharmaceutical&nbsp; products are necessary due to the drugs' extensive clinical potential as well as their potential side effects. The following&nbsp; article was introduced by presenting a mini-review of the different methods used for the quantitative determination of&nbsp; these drugs in order to encourage and facilitate collecting literature review for other researchers who will have studies&nbsp; related to the presented compounds. The review discussed techniques used for the determination of each drug quantitatively involving spectrophotometric (UV and visible), spectrofluorimetric, electrochemical and chromatographic&nbsp; (TLC and HPLC) methods either in a biological sample or in the pharmaceutical dosage forms. All methods included in&nbsp; the review are validated and constructed according to ICH guidelines.&nbsp;</p>

2023-11-10T00:00:00+00:00 Copyright (c) 2023 Faculty of Pharmacy; Zagazig University https://www.ajol.info/index.php/zjps/article/view/259006 2023-11-10T09:47:26+00:00 Abdulkader Memeh ph.d.abdulkader.memeh@gmail.com Abdel Galil Ghriwati ph.d.abdulkader.memeh@gmail.com Khalid Khanji ph.d.abdulkader.memeh@gmail.com Ibrahim Kebbe War ph.d.abdulkader.memeh@gmail.com

<p>Acute myeloid leukemia (AML) is a kind of hematologic malignancy in which overall survival (OS) may be affected by&nbsp; many factors such as the patient's age, gender, conventional karyotyping (CK) findings, lactate dehydrogenase (LDH)&nbsp; concentration, white blood cells (WBC) count, and bone marrow blast (BMB) percentage at diagnosis. In this study, we&nbsp; aimed to evaluate the prognostic significance of those characteristics on OS at diagnosis. The current study included 98 AML patients who have been examined for cytology, CK, and immunophenotyping. The average patient’s age was 39&nbsp; years old. In addition, around 56% of patients had a chromosomal abnormality. Furthermore, the patients with LDH&nbsp; levels higher than 450 IU/L, WBC counts over 50 X109/L, BMB% more than 50%, and AML-M0 had a shorter OS compared&nbsp; to other groups. However, the results suggested that CK, LDH, WBC count, and BMB% might be used as good&nbsp; prognostic tests in patients with AML at diagnosis.&nbsp;</p>

2023-11-10T00:00:00+00:00 Copyright (c) 2023 Faculty of Pharmacy; Zagazig University