Non-secretory multiple myeloma in a 37 year old pregnant woman in Owo: A case report

Abstract

Introduction: This is a case report of nonsecretory multiple myeloma in a young woman.

Case report: A 39-year old pregnant woman presented with chest pain, weight loss, generalized joint pain, body weakness, bilateral knee  joint swelling and fractures of the left humerus and distal femur. Investigations revealed leukocytosis, elevated plasma alkaline  phosphatase, negative serum protein electrophoresis and Bence Jones protein, anaemia and elevated erythrocyte sedimentation rate.  Skull X-ray showed motheaten appearance in keeping with myelomatosis. She had intrauterine foetal death; and was managed  subsequently as a case of non-secretory multiple myeloma with chemotherapy and had a tremendous improvement.

Conclusion: This  case illustrates the occurrence of patients with multiple myeloma who do not secrete immunoglobulins in our environment.