Estimation of cortisol levels in patient with Metabolic Syndrome in Al-Gorda Al-Shatti Region

Abstract

Metabolic Syndrome (MetS) is one of the most prevalent metabolic disorders, it is associated with cardiovascular disease (CVD), type 2 diabetes (T2DM) mellitus, and high blood pressure. This study was aimed to find out the incidence rate of MetS among people attending the combined clinic at Al-Qurdah Al-Shati area, according to the standards of the National Cholesterol Education Program's Adult Treatment Panel III (NCEP ATP III), also to measure the level of cortisol hormone and its relation to the factors of this syndrome. 158 subjects were recruited, ages ranging from 35-65 years, of both sexes (74 males and 84 females), divided into two groups (patients and control) depending on whether or not they had metabolic syndrome. Blood cortisol, fat, and glucose concentrations were measured for all of them. Data were analyzed statistically using the SPSS 20 program. Results showed that the incidence of metabolic syndrome was (58.23%), higher in females (52.17%) than males (47.83%), with the most affected ages being 55-65 years (47.83%). No significant difference in the level of cortisol hormone was found between patients and control, however, it was negatively correlated with Low-Density Lipoprotein (LDL) and cholesterol (P value < 0.05). To conclude there is a high prevalence of metabolic syndrome among the study population, which was more in females and older age groups, and cortisol hormone is not associated with the five factors of metabolic syndrome.