Pneumophonic Coordination Impairments in Parkinsonian Dysarthria: Importance of Aerodynamic Parameters Measurements

Abstract

Background: Among Parkinsonian axial signs, dysarthria represents an important disabling symptom able to lead towards a significant reduction of oral communication. Several methods of dysarthria assessment have been used but aerodynamic evaluation is rare in the literature.
Objective: To highlightthe importance of aerodynamic parameters measurements in assessment of parkinsonian dysarthria.
Patients and Methods: Using a dedicated system (EVA2), 24 parkinsonian patients were recorded after withdrawal of Ldopa for at least 12 h (condition called OFF DOPA) in order to evaluate intra-oral pressure (IOP), mean oral air flow (MOAF) and laryngeal resistance (LR) on six /p/ during realization of the sentence ‘‘Papa ne m’a pas parle´ de beau-papa’’ (‘‘Daddy did not speak to me about daddy-in-law’’) which corresponds to a breath group. 50 control subjects were recorded in parallel in order to define reference measurements.
Results: It appeared that there is in Parkinson’s disease aerodynamic impairments which were evidenced by the fall in IOP and that of MOAF in patients compared with control subjects. The difference between the two groups was statistically significant. In addition a greater instability of LR in patients compared with control subjects was also noted.
Conclusion:Our results show that measurements of aerodynamics parameters, by reflecting the dysfunction induced by disease, may well be relevant factors in parkinsonian dysarthria evaluation.

Keywords: Intra-oral pressure, Oral airflow, Laryngeal resistance, Parkinson’s disease, Dysarthria, Pneumophonic coordination, Aerodynamic evaluation.