Antibiogram of Candida Species using Different Susceptibility Testing Techniques: A Systematic Review

Abstract

Susceptibility pattern determination is a valuable key towards successful treatment of infectious diseases. Susceptibility of Candida species to different antifungal agents is also a common practice; however, different methods are employed to achieve the same goal. Some of the different techniques include disc diffusion method, Epsilometer test (E-test), Candfast, and microdilution technique, among others. Fluconazole, Voriconazole, Itraconazole, and Amphotericin B are some of the antifungal agents commonly used for the treatment of infections due to Candida species. Most of these antifungals are also covered in this review. The commonly encountered Candida species in clinical settings include: C. parapsilosis, C. tropicalis, C. albicans, C. krusei, and C. glabrata. This review also provides some insight into their variable susceptibility patterns as it affects different methods of susceptibility testing. There were reports of resistance from researchers from different regions across the globe; this, therefore, signifies the importance of the availability of data with regards to susceptibility of these species.