Article Sidebar
Article Details
Submission of a manuscript to this journal is a representation that the manuscript has not been published previously and is not under consideration for publication elsewhere.
All authors named in each manuscript would be required to sign a form (to be supplied by the Editor) so that they may retain their copyright in the article but to assign to us (the Publishers) and its licensees in perpetuity, in all forms, formats and media (whether known or created in the future) to (i) publish, reproduce, distribute, display and store the contribution, (ii) translate the contribution into other languages, create adaptations, reprints, include within collections and create summaries, extracts and/or abstracts of the contribution, (iii) create any other derivative works(s) based on the contribution, (iv) to exploit all subsidiary rights in the contribution, (v) the inclusion of electronic links from the contribution to third party material where-ever it may be located, and (vi) license any thrid party to do any or all of the above.
Main Article Content
Evaluation of the Antibacterial Activity of 14 Medicinal Plants in Côte d’Ivoire
Abstract
Purpose: To evaluate the antibacterial potentials of fourteen ethnobotanically selected plants traditionally used in different parts of Côte d’Ivoire for the treatment of typhoid fever and gastrointestinal disorders.
Method: The antimicrobial activity of the extracts of the plant was tested against a collection strain of Salmonella typhimurium, a clinical strain of Salmonella typhi and Pseudomonas aeruginosa by macrobroth dilution method. Minimum inhibitory concentration (MIC) and minimum bactericidal
concentration (MBC) were determined. Results: All the plants had bactericidal activity against at least one of the test microorganisms with both MIC and MBC ranging from 2.5 to > 80 mg/ml. Among the plant extracts, Terminalia glaucescens. (Combretaceae) Bersama abyssinica subsp. paullinioides (Melianthaceae ) and Abrus precatorius (Fabaceae) showed the most promising broad spectrum antibacterial properties, inhibiting all of the strains tested, especially S. Typhi and P. aeruginosa, with MBC ranging from 2.5 to 5 mg/ml. Conclusion: The findings provide support for the use of these plants in traditional medicine for treatment of typhoid fever and gastrointestinal disorders, and are thus, potential sources of drugs that would need to be subjected to further studies.
Keywords: Antimicrobial activity, Ivorian medicinal plants, MIC, MBC.
