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Feb 11, 2025Keywords:
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Main Article Content
An overview of the hypolipidemic effect of Genus Berberis
Abstract
Dyslipidemia is a chronic disease characterized by elevated blood lipid levels treatable with statins.
However, long-term statin use may have adverse effects, such as liver damage and memory loss.
Nevertheless, plants and their active compounds effectively and safely improve lipid profiles. This
review aims to update information on the genus Berberis as a hypolipidemic agent, assess the effects of
these extracts on organisms and provide evidence supporting the use of these natural products in
pharmaceutical drugs. Berberis species with therapeutic potential include B. vulgaris, B. integerrima, B.
aristata, B. lycium, B. orthobotrys, and B. calliobotrys, which have shown promising results in reducing
lipid levels in humans and other animals. In addition, combining berberine with nutraceuticals may
improve its intestinal absorption, enhancing its lipid-lowering effect. Herbal medicine studies suggest
that Berberis has a high potential for the management of hyperlipidemia.
