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Efficacy of Qingying decoction and Wuling powder in the treatment of renal hematuria: A traditional Chinese medicine approach


Rui Tao
Shuxiang Yu
You Lu
Lan Zhai
Hongsheng Zhang
Xiao Yang

Abstract

Purpose: To investigate the efficacy of combining Qingying decoction with Wuling powder in the treatment of renal hematuria.


Method: Seventy-six patients diagnosed with renal hematuria in the Emergency General Hospital and Nanmofang Community Health  Service Center in Chaoyang District of Beijing, China were randomized equally into study and control groups. Control group received  standard Western treatment in addition to Shenyan Rehabilitation tablets while study group received a combination of Qingying  decoction and a modified Wuling powder alongside standard treatment for eight weeks. Treatment effectiveness was evaluated using  urinary red blood cell count (URBC), urinary albumin-to-creatinine ratio (UACR), urinary β 2-microglobulin (β2-MG) and α 1-microglobulin  (α1-MG) levels, serum levels of complement components 3 (C3) and 4 (C4), immunoglobulin A (IgA), and Traditional Chinese Medicine  (TCM) syndrome scores.


Results: There was a significant difference in total therapeutic effectiveness between study and control groups  (p < 0.01). Study group showed significantly improved hematuria and total syndrome scores (p < 0.01). The study group showed  significantly lower URBC, UACR, β 2-MG, α 1-MG, IgA, and C3 levels compared to the control group (p < 0.05).


Conclusion: Treatment with  Qingying decoction and Wuling powder demonstrates efficacy in managing renal hematuria, regulates urinary red blood cell counts,  reduces symptoms, and lowers early renal impairment. Future studies in multiple centers using larger number of patients to determine  the mechanisms of these drug actions and interactions and other related factors would be required. 


Journal Identifiers


eISSN: 1596-9827
print ISSN: 1596-5996