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Mar 31, 2025Keywords:
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Main Article Content
Effect of ropivacaine concentrations in combined spinalepidural anesthesia on efficacy and sedation levels in lower abdominal obesity patients
Abstract
Purpose: To investigate the effect of varying ropivacaine concentrations in combined spinal-epidural
anesthesia (CSEA) on anesthetic efficacy and sedation in patients with lower abdominal obesity.
Methods: 110 patients with lower abdominal obesity who received CSEA in Traditional Chinese
Medicine Hospital, Lin 'an District, Hangzhou, China from January 2020 to December 2022 were
retrospectively enrolled. Patients were divided into a low-concentration group (LC group, n = 49) which
received 0.3 % ropivacaine, and a high-concentration group (HC group, n = 61) which received 0.5 %
ropivacaine. Changes in visual analogue scale (VAS) scores and Ramsay sedation scale (RSS) scores
in both groups were analyzed at 1, 2, 4 and 6 h after surgery.
Results: The LC group showed significantly higher static and dynamic VAS scores than HC group at 1,
2, 4 and 6 h after surgery. Furthermore, HC group demonstrated significantly shorter (p < 0.05) onset
times for sensory and motor blocks, longer sensory and motor recovery times, and lower mean arterial
pressure (MAP) level 10 min after administration compared to the LC group. However, MAP levels 30
min after administration were similar to baseline levels in both groups (p > 0.05).
Conclusion: High-concentration ropivacaine in CSEA offers superior post-operative analgesia, and
improves patient satisfaction without increasing adverse reactions in patients with lower abdominal
obesity. Further studies using larger sample size and longer duration of investigation are required to
strengthen the validity of these results.
