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Mar 31, 2025Keywords:
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Main Article Content
A meta-analysis of the efficacy of Buyang Huanwu decoction in the treatment of ischemic stroke
Abstract
Purpose: This meta-analysis was aimed at investigating the efficacy and safety of Buyang Huanwu
decoction in the management of ischaemic stroke.
Methods: Randomized controlled trials (RCTs) on the clinical efficacy of Buyang Huanwu decoction for
ischemic stroke patients were searched in PubMed, Cochrane Library, Embase, China Knowledge
Infrastructure (CNKI), China Science and Technology Journal Database and Wanfang Database. The
search period was from 1 January 2010 to 31 July 2023, and the parameters evaluated included
efficacy, limb motor function score, National Institutes of Health Stroke Scale (NIHSS) score, and
adverse drug reactions. Relevant data were extracted, assessed for quality, and analyzed using
RevMan 5.2.
Results: The inclusion criteria were met by nine RCTs, encompassing a total of 883 participants. The
meta-analysis revealed that Buyang Huanwu decoction significantly enhanced motor function recovery,
reduced neurological impairment, decreased the incidence of adverse reactions, elevated ADL scores,
and an overall increase in clinical effectiveness (p < 0.05). Additionally, there was a significant decrease
and increase in TCM symptom scores and FMA scores respectively (p < 0.05).
Conclusion: Buyang Huanwu decoction improves clinical outcomes and motor functions in patients
with ischaemic stroke. It is important to expand this study to include larger sample sizes, longer followup
periods, and a broader scope of literature to validate its findings.
