Main Article Content
Traditional uses, chemical constituents and pharmacological effects of Boschniakia rossica: A systematic review
Abstract
Purpose: To undertake a review on the morphology, traditional uses, phytochemistry and pharmacology of Boschniakia rossica, a plant with a long history of usage in Chinese traditional medicine.
Methods: Available literature on the ethnopharmacological uses of B. rossica from 1967 to 2018 were selected via various databases, such as ScienceDirect, NCBI, Springerlink, Taylor & Francis and CNKI.
Results: A variety of phytochemical studies demonstrated that B. rossica contains more than 100 chemical constituents, among which boschnaside, boschniakine, 7-deoxy 8-epiloganic acid, (4R)-4- hydroxymethyl-boschnialactone are predominant. Studies showed that isolates and crude extracts of B. rossica exhibit a wide spectrum of in vitro and in vivo pharmacological effects such as anti-aging, antitumor, anti-oxidant, anti-inflammatory and immune enhancement. It was revealed that iridoids, carbohydrates and glycosides are perhaps responsible for most of the biological activities shown by this plant. However, the bio-active compounds and their underlying mechanisms of action have not yet been investigated in detail.
Conclusion: B. rossia has received tremendous research attention. Phytochemical and pharmacological studies have provided scientific bases for validation of the traditional uses of the plant