Article Sidebar
Published:
Jan 13, 2017Keywords:
Article Details
Submission of a manuscript to this journal is a representation that the manuscript has not been published previously and is not under consideration for publication elsewhere.
All authors named in each manuscript would be required to sign a form (to be supplied by the Editor) so that they may retain their copyright in the article but to assign to us (the Publishers) and its licensees in perpetuity, in all forms, formats and media (whether known or created in the future) to (i) publish, reproduce, distribute, display and store the contribution, (ii) translate the contribution into other languages, create adaptations, reprints, include within collections and create summaries, extracts and/or abstracts of the contribution, (iii) create any other derivative works(s) based on the contribution, (iv) to exploit all subsidiary rights in the contribution, (v) the inclusion of electronic links from the contribution to third party material where-ever it may be located, and (vi) license any thrid party to do any or all of the above.
Main Article Content
Synthesis and evaluation of antioxidant and antimicrobial activities of Schiff base tin (II) complexes
Abstract
Purpose: To synthesize and evaluate Schiff base Tin (II) complexes for antioxidant and antimicrobial activities
Methods: The complexes of Tin (II) chloride with various Schiff base derivative of 2-Hydroxy-1- naphthaldehyde (HN) were synthesized and characterized by various physiochemical techniques, including elemental analysis, ultraviolet–visible (UV-Vis) spectrophotometry, Fourier transform infrared spectroscopy (FTIR), proton nuclear magnetic resonance (1H–NMR), carbon-13 nuclear magnetic resonance (13C-NMR), electron ionization mass spectrometry (EIMS) and conductance studies. Agarwell diffusion and agar-well dilution techniques were used for antimicrobial assessment. Evaluation of the antioxidant activity of the ligands and complexes was accomplished by DPPH radical scavenging assay.
Results: The results indicate coordination of deprotonated phenolic oxygen and nitrogen of azomethine with Tin (II) chloride led to the formation of stable complexes. The Tin (II) complexes showed good antimicrobial and antioxidant activities. Compounds (HNPA and [Sn(HNPA)Cl2(H2O)2) were noteworthy (p < 0.05) in this regard with antibacterial activity against Staphylococcus aureus, while [Sn(HNCA)Cl2(H2O)2 and [Sn(HNPT)Cl2(H2O)2 were active against Klebsiella pneumoniae..
Conclusion: All synthesized Schiff bases and their Tin (II) complexes showed high antimicrobial and antioxidant activities than their corresponding ligands.
Keywords: Schiff base, Ligand, Tin (II) complexes, Antimicrobial, Antioxidant, Deprotonated phenolic oxygen
