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Jul 31, 2007Keywords:
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Efficacy of artemether-lumfantrine (Co-Artesiane®) suspension in the treatment of uncomplicated Plasmodium falciparum malaria among children under 5 years in eastern Sudan
Abstract
Purpose: the aim of the present study was to investigate the efficacy of artemether-lumfantrine (Co-Artesiane®) suspension for the treatment of uncomplicated Plasmodium falciparum malaria in children (aged 6-59 months) in Kassala in eastern Sudan.
Method: This was a prospective clinical trial where the artemether-lumfantrine (Co-Artesiane®) suspension was given for three days and the patients were followed-up for 28 days
Results: Forty-eight patients were enrolled in the study and 43 of them completed the 28-days follow-up. Treatment rapidly cleared parasitemia and fever. The overall 28-day cure rate was 100% and no clinical or parasitological failures were observed among these patients. Mild side effects were observed in three (7%) children.
Conclusion: Artemether-lumfantrine (coartem) suspension appears to be efficacious and safe for the treatment of uncomplicated malaria.
Keywords: Artemether-lumfantrine, Co-Artesiane, children, falciparum, malaria, Sudan
> Tropical Journal of Pharmaceutical Research Vol. 5 (1) 2006: pp. 551-555
