Pregnancy loss: a rare consequence of premenstrual endometrial curettage for infertility management

Abstract

Two cases of pregnancy loss - a rare complication of pre-menstrual endometrial biopsy (PMEB) are reported. PMEB is an investigation performed for infertile women to assess ovulation and endometrial factors. It is usually performed during the secretory phase of the cycle. This implies that ovulation and possibly fertilization may have taken place. In the two patients presented, histology report in one suggested pregnancy while the second presented with massive vaginal bleeding few days after PMEB requiring evacuation. The histology of the latter confirmed products of conception. Though PMEB is useful, it may lead to pregnancy loss. Couples should be counseled to avoid sex during the fertile days of the cycle scheduled for PMEB investigation. Wider availability and use of ultrasonography to assess ovulatory factor may avert this painful complication.

Keywords: pregnancy, abortion, infertility, curettage

Tropical Journal of Obstetrics and Gynaecology Vol. 22(1) 2005: 74-75