Antibacterial activity of crude N-butanol fraction of Terminalia avicenoides

Abstract

Eight gram of the primary extracts was fractionated using N-butanol. Preliminary phytochemical screening and antibacterial activity was determined. Qualitative analysis of the extracts revealed the presence of glycosides, saponins, tannins, flavonoids, alkaloids, steroids and phenol. Different concentrations ranging from 10mg/ml to 50mg/ml were used to test the antibacterial activity. Result of the study showed that the fraction is active against Methicillin Resistant Staphylococcus aureus with the means zone of inhibition ranging from 14.50±0.02^e to 22.00±0.06^a. Zones of inhibition were measured in millimeter to the nearest whole number using meter rule.