Analyse comparative du profil épidémiologique et clinique de l'infection grippale due aux virus pH1N1(2009), H1N1, H3N2 et B à Abidjan, Côte d'Ivoire

Abstract

English Title: Comparative analysis of the epidemiological and clinical profiles of influenza infection due to 2009 pH1N1, H1N1, H3N2 and B viruses in Abidjan, Cote d'Ivoire

English Abstract

Influenza can have various epidemiological and clinical characteristics. This study compares the epidemio-clinical profiles of influenza infections related to different viruses in the population of Abidjan. A review of surveillance data (2007-2010) on influenza was performed. We used Chi2 test to compare proportions and simple linear regression and sequential logistic regression models for prediction profiles on Stata 12 software. In tota1529 cases of influenza infection were recorded, including 60 cases of H1N1 (11.3% ), 177 cases ofH3N2 (33.5%), 34 cases of pH1N1 (6.4%) and258 cases of influenza B (48.8%). Fever prevailed  with H1N1 (76.1 %). The patients with pH1N1 were more likely to have cough (OR= 10.52, 95% CI: 1.713-64.575; versus H1N1) and to be from the age group of 5-14 years (OR= 3.10, 95% CI: 1.316-7.301; versus influenza B). For patients with influenza H3N2, cough (OR = 6.3, 95% CI: 2.466-16.347) and arthralgia/myalgia (OR= 2.54, 95% CI: 1.083-5.948) were the best predictors (versus influenza H1N1). The identification of specific profiles in our study can improve the method of diagnosis and surveillance of influenza.

Keywords: Influenza Infection, epidemio-clinical profiles, Abidjan, Cote d'Ivoire