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Dec 2, 2024Keywords:
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Sokoto Journal of Medical Laboratory Science (SJMLS) is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. The journal holds the copyright for all the published articles. The signed copyright form submitted by the authors is a publication agreement between the journal and the authors.
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Impact of combined aqueous extracts of Turmeric and Curry leaf on the reproductive parameters of high salt fed male Wistar rats
Abstract
Infertility poses a significant challenge affecting millions of couples worldwide, with oxidative stress (OS) emerging as a key contributor, particularly in cases of idiopathic male infertility. This study investigated the potential therapeutic effects of combined aqueous extracts of Turmeric and Curry leaves (TCL) on reproductive parameters in high salt-fed male Wistar rats. Thirty-six rats were randomly assigned to six groups and subjected to varying interventions over a 28-day period. Sperm parameters including testosterone levels, and histological changes in testicular tissues were evaluated. Results revealed that high salt intake negatively impacted sperm quality, viability, and testosterone levels, while TCL extracts demonstrated dose-dependent improvements in these parameters. Histological analysis demonstrated varying degrees of testicular tissue distortion across groups, with TCL extracts showing protective effects against high salt-induced damage. These findings suggest that TCL extracts have potential therapeutic benefits in mitigating the adverse effects of high salt intake on male reproductive health. Further research is recommended to elucidate the underlying mechanisms and optimize the application of TCL extracts as a promising intervention for preserving fertility amidst dietary challenges.
