Sister Mary Joseph’s nodule as the first presentation of gallbladder carcinoma: A case report and literature review

Abstract

Metastatic umbilical deposits from abdominal and pelvic malignancy is termed Sister Mary Joseph’s nodule. Metastasis of gallbladder adenocarcinoma to the umbilicus is extremely rare, even rarer is for this metastasis to be the initial presentation of gallbladder carcinoma. We report a case of gallbladder
carcinoma presenting as sister Mary Joseph’s nodule. Physicians should consider this type of metastasis in patients presenting with umbilical nodules and biopsy should always be obtained.