Article Sidebar
Article Details
Issue
Section
Articles
Copyright for articles published in this journal is retained by the journal.
This content is freely available and published under a Creative Commons Attribution License.
Main Article Content
The use of nasal midazolam in reducing preoperative anxiety in children
Abstract
Background: Surgery and anesthesia can cause a considerable distress with psychological consequences for children. This preoperative anxiety can lead to post operative emergence delirium, maladaptive behavioral changes such as night time crying, enuresis, feeding difficulties, apathy, and withdrawal.
Objectives: The aim of this study is to investigate the effect of nasal midazolam as a routine intervention to reduce pre-operative anxiety and inducing anxiolysis in children undergoing day case procedure.
Method: One hundred children were randomly allocated into two groups. The study group (N=50) were premedicated with nasal midazolam 0.2mg/kg and the control group (N=50) who received 0.04ml of normal saline. The children response to nasal administration was noticed and after 15 minutes children were taken to operating room. Anxiety at parental separation and at induction of anesthesia was measured using modified-Yale Preoperative Anxiety Scale.
Results: Children who received nasal midazolam had a significantly better parental separation and induction of anesthesia. 88% of children who received nasal midazolam scored below 30-indicating absence of anxiety- on modified-Yale Preoperative Anxiety Scale compared to 32% in the control group. More than half of patients in both groups found nasal route to be unpleasant and stressful.
Conclusion: For children undergoing elective brief surgical procedure, nasal midazolam is effective in reducing preoperative anxiety. Nasal midazolam was associated in more than half of patients with nasal irritation and crying, a route can not be recommended in children.
Objectives: The aim of this study is to investigate the effect of nasal midazolam as a routine intervention to reduce pre-operative anxiety and inducing anxiolysis in children undergoing day case procedure.
Method: One hundred children were randomly allocated into two groups. The study group (N=50) were premedicated with nasal midazolam 0.2mg/kg and the control group (N=50) who received 0.04ml of normal saline. The children response to nasal administration was noticed and after 15 minutes children were taken to operating room. Anxiety at parental separation and at induction of anesthesia was measured using modified-Yale Preoperative Anxiety Scale.
Results: Children who received nasal midazolam had a significantly better parental separation and induction of anesthesia. 88% of children who received nasal midazolam scored below 30-indicating absence of anxiety- on modified-Yale Preoperative Anxiety Scale compared to 32% in the control group. More than half of patients in both groups found nasal route to be unpleasant and stressful.
Conclusion: For children undergoing elective brief surgical procedure, nasal midazolam is effective in reducing preoperative anxiety. Nasal midazolam was associated in more than half of patients with nasal irritation and crying, a route can not be recommended in children.
