Proportion of bacteria causing healthcare associated infection in Khartoum North Teaching Hospital

Abstract

Background: This study was conducted at Khartoum North Teaching Hospital (KNTH) in the period between June 2005 to September 2007 in order to determine the bacteria that causes common healthcare associated infection (HAI.) Methods: Hundred bacteriological specimens from patients with HAI from different surgical and internal medicine departments (27 from patients in obstetrics and gynecology units, 33 from patients in surgical ward, and 16 from urology units, 12 from the medicine, 8 from the otorhinolaryngyology and 4 from ophthalmology departments) were collected. All samples were cultured on suitable bacterial culture media and processed. Presence of significant growth was further studied to identify type of pathogen and its susceptibility against selected (common used)
antibiotics. Results: Study showed that the most frequent bacteria isolated from patients as a cause of HAI were Pseudomonas aeruginosa (23%) , Proteus mirabilis (17%) , and E. coli (13%) respectively. Conclusion: The study also revealed that all Gram-negative isolates were highly sensitive to antibiotic such as ceftriaxone, ciprofloxacin and imipenem, while P. aeruginosa showed resistant to many commonly used antibiotics, but was sensitive to imipenem and pipracillin. All Gram-positive isolates were sensitive to vancomycin. Further studies are needed to evaluate the common microorganisms causing HAI and their drug susceptibility and proportion of HAI in this setting.

Keywords: Gram-negative, Gram-positive, Nosocomial, microorganisms, antibiotic resistance.