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A double-blind gastroscopic study of a bismuth-peptide complex in gastric ulceration
Abstract
Forty courses of treatment with bicitropeptide (BCP) were administered to 30 patients with gastric ulcers, in a double-blind crossover trial. Healing was judged gastroscopically after 4 weeks, at which time 79% of ulcers had healed on BCP and 35% on placebo (P<0,01). There were no side-effects. Bicitropeptide is a bismuth-protein complex, active at a pH of less than 4. A protective 'protein-bismuth complex' layer is said to be formed over the ulcer.
S. Afr. Med. J., 48, 1610 (1974)
S. Afr. Med. J., 48, 1610 (1974)