Main Article Content

Orudis in the management of osteo-arthritis of the knee


L. Solomon
G. Abrams

Abstract

A controlled double-blind crossover trial of Orudis, a nonsteroid anti-inflammatory drug, has been car.ried out in 98 patients with osteo-arthritis of the knee. The new preparation was tested against placebo (27 patients), paracetamol (42 patients) and acetylsalicylic acid (29 patients). It showed statistically significant superiority over placebo (P<0,05). Compared with paracetamol, the over-all results showed a marked trend in favour of Orudis, though this did not reach statistical significance (0,1>P>0,05). On the principal criteria for assessment there was no significant difference between Orudis and high-dosage salicylate (P<0,05); most of the patients, however, favoured the former.

S. Afr. Med. J. 48, 1526 (1974).

Journal Identifiers


eISSN: 2078-5135
print ISSN: 0256-9574