Main Article Content

Low-dosage clomiphene therapy in the treatment of infertility due to defective ovulation


C.T.H. Barrett

Abstract

The use of clomiphene in gradually increasing doses, in cases of infertility due to anovulation, oligo-ovulation and inadequate luteal phase, led to a high pregnancy rate, particularly in the initial stages of treatment. Although clomiphene is a relatively safe and inexpensive drug, there is a possibility that high doses in repeated cycles may adversely affect fertility by its anti-oestrogenic effect. It is therefore suggested that therapy be commenced with a lower dosage than that generally recommended.

S. Afr. Med. J., 48, 1456 (1974).

Journal Identifiers


eISSN: 2078-5135
print ISSN: 0256-9574