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Perhexiline maleate in the management of patients with angina pectoris


N. Gitlin

Abstract

In a single-blind study lasting 6 months an entirely new anti-anginal preparation, perhexiline maleate (Pexid), was prescribed in a dose of 200 mg b.d. to 21 patients suffering from angina pectoris. There was a statistically significant reduction in the average number of anginal attacks over the 6-month period in each subgroup studied. Half the cases studied were asymptomatic at the end of the period. Side-effects were reported in 16 patients; dizziness, headache, weakness, loss of weight and decreased libido being the commonest symptoms. No patient withdrew from the trial because of these symptoms, which disappeared within 4 weeks of continued therapy.

S. Afr. Med. J., 48, 904 (1974).

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eISSN: 2078-5135
print ISSN: 0256-9574