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Carcinoma of the thyroid following irradiation of the neck
Abstract
It is 8 years since Duffy and Fitzgerald's important observation that there might be some relation between therapeutic irradiation of the chest in infancy and childhood and the subsequent development of cancer of the thyroid. Since then a number of reports have appeared confirming their postulates. Stewart et al found an increased incidence of cancer, including leukaemia, in children whose mothers had had X-ray examinations of the abdomen during pregnancy. With evidence accumulating that carcinogenesis may result from exposure to X-rays, we report a case of papillary carcinoma of the thyroid in an African girl of 12 years developing 7 years after she had received irradiation for a lymphosarcoma of the neck.