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Motor neuropathy appearing during the course of treated tuberculous meningitis
Abstract
Isonicotinic acid hydrazide has now been in use for over 5 years in the treatment of tuberculosis in its various forms. Many toxic effects of the drug have been reported, including a number of cases of peripheral neuritis. This paper deals with a patient suffering from tuberculous meningitis who developed a lowermotor- neurone lesion during the course of treatment. The problems to decide were, firstly, whether the neuropathy was part of the disease or was due to one of the antituberculous drugs; secondly, whether or not to continue with the antituberculous therapy,