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A Comparison between Oral Pivampicillin and Ampicillin in Children with Bronchopneumonia


J.G. Prinsloo
A. Cicoria
R.G. Robinson
N.F. Laubscher

Abstract

Pivampicillin and ampicillin were compared, in 30 children suffering from acute bronchopneumonia, as regards intestinal absorption, liver function tests and clinical response. No significant differences were found in the clinical response or liver function tests of the two groups. Enteral absorption of pivampicillin was significantly better than that of ampicillin. It is concluded that pivampicillin should be theoretically superior to ordinary ampicillin in the oral treatment of infections due to ampicillin-sensitive micro-organisms.


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eISSN: 2078-5135
print ISSN: 0256-9574