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Comparison of oral glucose-tolerance tests and serum insulin responses in pellagra and kwashiorkor
Abstract
Oral glucose-tolerance tests were conducted and the serum insulin responses were measured on admission as well as after clinical recovery in 8 pellagious children and 12 with kwashiorkor. There were wide variations in the response of individual patients, but, on the whole, the kwashiorkor group had a more disturbed glucose tolerance and poorer insulin response than the pellagra group. Average fasting serum insulin levels were higher than those reported for normal children and the insulin response increased from admission to recovery. No significant differences were found between the 2 groups (on admission as well as after recovery), or between the vaues of the same group from admission to recovery.
