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Pyrantel Pamoate in Roundworm Infestations
Abstract
A controlled single-blind trial was carried out to compare the effect of single-dose therapy with pyrantel pamoate (Combantrin) and piperazine citrate in children infested with Ascaris lumbricoides. Fifty-six children were treated. Pyrantel pamoate was 96,4% effective and piperazine c::itrate 82,1% effective in eradicating Ascaris lumbricoides. ova from 3 consecutive stools taken on the 7th, 8th and 9th days after treatment. If results of stool examination on the 9th day only are considered, pyrantel pamoate was 100% effective and piperazine citrate was 89,3% effective.
S. Afr. Med. J., 47, 91 (1973)