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Antibodies Against Melanin


HP Wassermann
JJ van der Walt

Abstract

This study reports on unsuccessful attempts to produce antibodies against melanoprotein in rabbits. Available evidence suggests antibodies against melanocytes in the aetiology of vitiligo, but there is no convincing evidence for antibodies against melanin per se. It is suggested that the demonstration of antibodif's against an immune serum, obtained from rabbits after injection of a melanoma homogenate (which contained cell debris), may be due to antibodies against unmelanized or incompletely melanized melanosomes.

S. Air. Med. J., 47, 7 (1973).

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eISSN: 2078-5135
print ISSN: 0256-9574