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Inflammatory bowel disease in Cape Town, 1975-1980 Part n. Crohn's disease


J.P. Wright
I.N. Marks
Celia Jameson
J.A.M. Garisch
D.G. Burns
R.E. Kottler

Abstract

Patients with Crohn's disease seen in the Gastrointestinal Clinic of Groote Schuur Hospital between 1975 and 1980 were studied to establish the incidence and clinical features of this disease. There were 117 patients and the mean (± SEM) follow-up was 6,1 ± 0,5 years. Of these patients 72% were White, 37% Coloured and 1% Black. The incidence for the Coloured and White population groups was calculated to be 0,4 and 0,9/100000 per year during 1970-1974 and 1,3 and 1,2/100000 per year during 1975-1980 respectively. In Jews the rates were 5,0 and 7,2/100000 per year forthe two periods. Insufficient data are available to calculate an incidence for the Black population. The disease involved the ileum in 39%, the colon in 17%and both areas in 44% of patients. At presentation 18% of patients had mild, 37% moderate, and 45% severe disease. The severity of symptoms was not related to the extent of the disease. A peri-anal fistula was present in 24% of patients. There was no difference in clinical features between the different population groups. Surgical resection had been performed in 50% of patients and 29% of these had had two or more resections. The surgical rate in the ileitis group was 63%, in the ileocolitis group 49% and in those with colitis 20%.


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eISSN: 2078-5135
print ISSN: 0256-9574