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An analysis of DTPassociated reactions by manufacturer, batch, vaccinator, series number and infant weight
Abstract
Objectives. To detennine whether two commonly used DTP batches manufactured by Rh6ne-Poulenc Rorer were more reactogenic than two commonly used batches manufactured by the South African Institute of Medical Research.
Design. Prospective study.
Setting. Six community clinics.
Patients. Infants routinely scheduled for their first three DTP immunisations.
Main outcome measures. Local and systemic adverse reactions following immunisation with DTP.
Results. Local reactions were significantly more common with both Rh6ne--Poulenc Rarer products.
Conclusion. AJI adverse reaction rates compared favourably with those reported by the Centers for Disease Control.
