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Nov 23, 2016Article Details
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Main Article Content
Comparison between the Acarex R test and a Der p 1 ELISA for the detection of house-dust mites in the homes of asthtma sufferers
Abstract
Exposure to house-dust mite allergens in early childhood is an important determinant of the subsequent development of asthma. The Acarex R semi-quantitative test (Noristan) is marketed for use in patients' homes to assess mite levels in house dust. In order to evaluate the reliability of the test in a coastal area where house-dust mites are known to be prevalent, house-dust mite levels were estimated in 119 dust samples obtained from the homes of asthmatic children in a comparative study, by means of the Acarex R test and a Der p 1 enzyme-linked immunosorbent assay (EUSA). A linear regression of the 4 Acarex classes against log Der p 1 revealed a significant correlation (P = 0,0001) but there was a poor correlation between low Acarex R scores and the Der p 1 allergen levels determined by EUSA. Acarex R scores of 2 and 3 were usually associated with Der p 1 levels greater than 10µg/g dust.
