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The neurocysticercosis project in Atteridgeville - Mamelodi townships


N A Mafojane

Abstract

The incidence and prevalence of neurocysticercosis in South Africa are unknown. A hospital-based prospective study to deternrine the incidence of neurocysticercosis was therefore undertaken. A research questionnaire and strict inclusion and
exclusion criteria were used. Apart from determining the incidence, our other aims were to determine the sources of infection and routes of transmission, evaluate therapeutic programmes and, on the basis of our findings, develop prevention
programmes. We found that it was impossible to determine the sources of infection and routes of transmission. When strict selection criteria were applied the number of patients (13) was significantly smaller than the 58 patients in an earlier pilot project. The implications of the findings for incidence surveys are discussed. The implications of the enzyme-linked immunosorbent assay (EUSA) ofserum and cerebrospinal fluid for diagnosis are discussed. The effectiveness of praziquantel was confirmed, and therapeutic approaches and preventive measures based on our findings are suggested.


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eISSN: 2078-5135
print ISSN: 0256-9574