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Jan 23, 2008Article Details
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Main Article Content
The utility of thrombo-elastography in the monitoring of aspirin therapy
Abstract
To assess the utility of the thrombo-elastogram in monitoring of aspirin therapy 25 healthy volunteers were selected and given low-dose aspirin therapy. Thrombo-elastography and platelet aggregometry were conducted at baseline and 1 week
later. After 1 week of aspirin therapy, thrombo-elastogram data failed to demonstrate a significant change in the clotting profile. Platelet aggregometry identified significant changes in the clotting profile in response to stimulation with arachidonic acid, adrenaline and ADP.
We conclude that thrombo-elastography may not have utility in monitoring of response to aspirin.
South African Medical Journal Vol. 97 (12) 2007: pp.1289-1291
