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Mar 16, 2016Article Details
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Main Article Content
Aetiology and outcome of severe community-acquired pneumonia in children admitted to a paediatric intensive care unit
Abstract
Objective. To determine the aetiological agents and outcome of severe community-acquired pneumonia (SCAP) in children admitted to the paediatric intensive care unit (PICU) at Kalafong Hospital, Pretoria.
Patients and methods. An audit was done after a protocol was implemented to identify the aetiological agents in children with life-threatening SCAP admitted to the PICU from the emergency room. The following investigations were done as per protocol: blood culture, culture of the tracheal aspirate, immunofluorescence and culture of the nasopharyngeal aspirate, microscopy and culture of the gastric juice for Mycobacterium tuberculosis, and determination of HIV status. The following data, documented prospectively, were obtained from patient records: date of admission, age, gender, weight, duration of ventilation, duration of stay in the PICU, survival or death, and severity of illness as determined by means of the score for acute neonatal physiology (SNAP) or paediatric risk of mortality (PRISM) score depending on the child's age.
Results. Twenty-three children were admitted over a 1-year period (1 November 1994-30 October 1995). Their median age was 10 weeks (range 2 weeks- 5 years) and the sex distribution was equal.
Two children were HIV-infected. Twenty children received mechanical ventilation for a median period of 6.5 days (range 2- 16 days). Aetiological agents were identified in 15/23 children (65%).
Respiratory syncytial virus (RSV) was the most common pathogen, identified in 7/23 children. Klebsiella pneumonia was the most common bacterial pathogen, identified in 5 children (2 blood cultures and 3 tracheal aspirates).
