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Coagulation for the clinician
Abstract
The integrity of the circulation is maintained through the provision of a rapid, potent, but tightly localised coagulation response to vascular damage. There is, however, one extraordinary problem in the regulation of haemostasis – blood flows. Normal haemostasis is the ability of the haemostatic system to control activation of clot formation and clot lysis in order to prevent haemorrhage without causing thrombosis.
South African Journal of Surgery Vol. 44 (1) 2006: pp. 22-37