Disparity in oesophageal cancer management in South Africa: a comparison between two tertiary centres with special focus on the palliation of dysphagia

Abstract

Background: For most patients with oesophageal cancer worldwide, palliation of dysphagia is the goal which is most commonly achieved with self-  expanding metal stents (SEMS). The aim of this study was to assess the profile and management of oesophageal cancer patients at Frere Hospital in the  Eastern Cape, and compare this to a similar cohort from Groote Schuur Hospital (GSH) in the Western Cape Province.

Methods: This study is a retrospective comparative cohort which reviewed all patients diagnosed with oesophageal cancer by the Frere Hospital and GSH  endoscopy units from January to December 2015. Independent prospective electronic databases for the two hospitals were merged for comparative  analysis.

Results: During the study period, 346 and 108 patients were diagnosed with oesophageal cancer at Frere Hospital and GSH respectively. The rate of  curative intended intervention was similarly low, with 3% of cases at Frere Hospital undergoing oesophagectomy or definitive radiotherapy as compared  to 5% at GSH (p=0.48). In terms of palliation, significantly more patients received palliative oncological therapy at GSH as compared to Frere Hospital (21%  vs 8%, p < 0.001). At Frere Hospital, 281 patients (81%) were treated primarily with serial dilatations. At GSH, 9 patients received a single dilatation, all as a bridge to radiotherapy or stenting. At Frere Hospital, 28 patients (8%) were stented, as compared to GHS where 69 patients (64%) were managed  with a stent (p < 0.001).

Conclusion: This study shows significant differences in the oncological and endoscopic palliation of patients between the two institutions, highlighting a  gross disparity in healthcare provision between them. The reasons for these disparities should be investigated and equipoise addressed by national  health policy makers.