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The enigma of reversible splenial lesions
Abstract
been described in a number of clinical paradigms. Epilepsy and related
conditions are the most commonly reported underlying clinical association.
Sudden anti-epileptic therapy withdrawal or seizure activity may be presumed to be the predisposing cause. However, an individual
susceptibility must also be considered. Although the exact mechanism
producing this syndrome is not known, the MRI appearance and course
in each of these clinically distinct causative entities is similar. The complete reversibility of the abnormality on follow-up studies is common
to all, and many authors suggest that a conservative watchful approach
is all that is required. We present here the findings in two patients with
similar, completely reversible, splenial lesions.
