Article Sidebar
Published:
Feb 27, 2019Article Details
Issue
Section
Articles
Material submitted for publication in the South African Journal of Obstetrics and Gynaecologyl (SAJOG) is accepted provided it has not been published elsewhere. Copyright forms will be sent with acknowledgement of receipt and the SAJOG reserves copyright of the material published.
The SAJOG does not hold itself responsible for statements made by the authors.
Main Article Content
Gestational outcomes of patients with multiple sclerosis: A tertiary centre experience
Abstract
Background. Multiple sclerosis (MS) is a disease that predominantly affects the young female population. It is important for an obstetrician to know the effects of pregnancy on MS, and vice versa.
Objective. To demonstrate the impact of MS on pregnancy outcomes.
Methods. We retrospectively evaluated demographic features, clinical characteristics, and obstetric outcomes of 47 pregnancies in 24 patients with MS, between January 2007 and December 2016.
Results. Patients were divided into three groups: (i) 35 pregnancies in patients with MS who were in remission at the beginning of pregnancy; (ii) 10 pregnancies in patients with MS whose disease was exacerbated at the beginning of pregnancy; and (iii) 2 pregnancies in patients with active MS whose symptoms were relieved after becoming pregnant. The overall early pregnancy loss rate was 36.2%, whereas it was 60% and 31.4% in the exacerbation and remission groups, respectively; and the overall preterm delivery rate was 30%, while it was 29.1% and 50% in the remission and exacerbation groups, respectively.
Conclusion. Miscarriage and preterm delivery seem to be significant obstetric complications in pregnant women with MS.
Objective. To demonstrate the impact of MS on pregnancy outcomes.
Methods. We retrospectively evaluated demographic features, clinical characteristics, and obstetric outcomes of 47 pregnancies in 24 patients with MS, between January 2007 and December 2016.
Results. Patients were divided into three groups: (i) 35 pregnancies in patients with MS who were in remission at the beginning of pregnancy; (ii) 10 pregnancies in patients with MS whose disease was exacerbated at the beginning of pregnancy; and (iii) 2 pregnancies in patients with active MS whose symptoms were relieved after becoming pregnant. The overall early pregnancy loss rate was 36.2%, whereas it was 60% and 31.4% in the exacerbation and remission groups, respectively; and the overall preterm delivery rate was 30%, while it was 29.1% and 50% in the remission and exacerbation groups, respectively.
Conclusion. Miscarriage and preterm delivery seem to be significant obstetric complications in pregnant women with MS.
