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Development and implementation of an HIV/AIDS trials management system: A geographical information systems approach
Abstract
Introduction. Researchers, practitioners and policymakers make decisions at all levels – from local to international. Accessible, integrated and up-to-date evidence is essential for successful and responsive decision-making. A current trials register of randomised and clinically controlled trials of HIV/AIDS interventions can provide invaluable
information to decision-making processes. Using the newly emerging geographical information systems (GIS) technology, we have developed a tool which assists such decisions. Objective. To demonstrate how the tool provides consistent, quantitative information in an accessible format, making it a key tool in evidence-based decision-making.
Methods. We identified all HIV/AIDS trials in relation to publications for the period 1980 - 2007, using both electronic and manual search methods. To facilitate searching the trials register, studies were coded by using a comprehensive but user-friendly coding sheet. We captured the geographical co-ordinates for each trial and used the ArcGIS 9 mapping software to design and develop a geodatabase of trials. Results. The geodatabase delivered the complete requirements for a data-driven information system, featuring
the following functions: (i) a clear display of the spatial distribution of HIV/AIDS trials around the world; (ii) identification of and access to information about any particular trial on a map; and (iii) a global resource of potential information on the safety and efficacy of prevention and treatment measures. Conclusions. The building of a functioning HIV/AIDS trials management system can provide policymakers, researchers and practitioners with accessible, integrated and up-to-date evidence that is essential to successful and
dynamic decision-making.
Southern African Journal of HIV Medicine Vol. 9 (2) 2008: pp. 58-62
