Article Sidebar
Published:
Jan 29, 2009Article Details
The author(s) retain copyright on work published by AOSIS unless specified otherwise.
Licensing and publishing rights
Author(s) of work published by AOSIS are required to grant AOSIS the unlimited rights to publish the definitive work in any format, language and medium, for any lawful purpose. AOSIS requires journal authors to publish their work in open access under the Creative Commons Attribution 4.0 International (CC BY 4.0) licence.
Read more here: http://creativecommons.org/licenses/by/4.0/.
The authors retain the non-exclusive right to do anything they wish with the published article(s), provided attribution is given to the applicable journal with details of the original publication, as set out in the official citation of the article published in the journal. The retained right specifically includes the right to post the article on the authors’ or their institution’s websites or in institutional repositories.
Previously published work may have been published under a different licence. We advise the community that if they would like to reuse the work to consult the applicable licence at article level.
Main Article Content
Changing antiretroviral therapy in paediatric patients
Abstract
An important principle in treating patients with HIV is that the first regimen is your best chance for success. So get it right the first time. Historically children have always lagged behind adults in their (virological) response to antiretrovirals (ARVs).1-3
However, with improvements in knowledge about pharmacokinetics, adherence and newer more potent and tolerable drugs in children, response to therapy in children is now approximating that in adults.4-6 Nevertheless, it is inevitable that over time, for
a variety of reasons, a significant number of patients will need to move to a second-line regimen. For this reason, it is important that we have an approach to changing therapy.
Southern African Journal of HIV Medicine Vol. 6 (4) 2005: pp. 38-42
